p63 protein is essential for the embryonic development of vibrissae and teeth.

@article{Rufini2006p63PI,
  title={p63 protein is essential for the embryonic development of vibrissae and teeth.},
  author={Alessandro Rufini and Miguel Weil and Frank McKeon and Alberto Barlattani and Gerry Melino and Eleonora Candi},
  journal={Biochemical and biophysical research communications},
  year={2006},
  volume={340 3},
  pages={737-41}
}
Development of skin appendages strongly depends on epithelial-mesenchymal interactions. One of the genes involved in this process is p63, a member of the p53 family of transcription factors, essential for ectodermal development, as elucidated by the phenotype of p63 knock-out mice. Surprisingly, no information on p63 expression in tooth and hair is yet available. Here, we show p63 expression during teeth and vibrissae morphogenesis in mouse embryos and we also show a correlation with the… CONTINUE READING

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