p63 immunohistochemistry differentiates salivary gland oncocytoma and oncocytic carcinoma from metastatic renal cell carcinoma.

@article{McHugh2007p63ID,
  title={p63 immunohistochemistry differentiates salivary gland oncocytoma and oncocytic carcinoma from metastatic renal cell carcinoma.},
  author={Jonathan McHugh and Aaron P. Hoschar and Mari Dvorakova and Anil V. Parwani and Ellen Barnes and Raja R Seethala},
  journal={Head and neck pathology},
  year={2007},
  volume={1 2},
  pages={123-31}
}
Metastatic renal cell carcinoma (RCC) can pose diagnostic challenges in the head and neck often resembling benign and malignant oncocytic lesions. Immunohistochemical panels have been reported to help with this differential but are not entirely specific or sensitive. We have noticed that p63 routinely stains salivary gland oncocytomas but not metastatic RCC. Nineteen oncocytomas, 9 cases of oncocytosis, 9 oncocytic carcinomas and 16 head and neck metastatic RCC were studied. Morphologic… CONTINUE READING