p53 tumour suppressor gene mutations in benign prostatic hyperplasia and prostate cancer.

@article{Schlechte1998p53TS,
  title={p53 tumour suppressor gene mutations in benign prostatic hyperplasia and prostate cancer.},
  author={Horst H Schlechte and Severin V Lenk and Thomas Loening and Dietmar Schnorr and Birgit D Rudolph and G. Ditscherlein and Stefan A. Loening},
  journal={European urology},
  year={1998},
  volume={34 5},
  pages={433-40}
}
OBJECTIVES To identify and analyse point mutations in p53 tumour suppressor gene (Tp53) in benign prostatic hyperplasia (BPH) by temperature gradient gel electrophoresis (TGGE) and sequence. MATERIALS AND METHODS 141 tissue specimens (approx. 100 mg) after transurethral resection of the prostate (TURP), 12 specimens after needle biopsy. Control samples… CONTINUE READING