p53 protein overexpression in gallbladder carcinoma and its precursor lesions: an immunohistochemical study.

@article{Wistuba1996p53PO,
  title={p53 protein overexpression in gallbladder carcinoma and its precursor lesions: an immunohistochemical study.},
  author={Ignacio Wistuba and Adi F. Gazdar and Ivan S. Roa and Jorge Albores-Saavedra},
  journal={Human pathology},
  year={1996},
  volume={27 4},
  pages={360-5}
}
Gallbladder carcinoma is one of the most frequent neoplasms diagnosed in Chile. Although the premalignant lesions have been extensively studied and are well characterized, there is only limited information about the genetic abnormalities that might be important in the pathogenesis of gallbladder carcinoma or that might have prognostic implications. The present study evaluates the immunohistochemical expression of p53 protein in premalignant lesions and invasive carcinoma of the gallbladder, and… CONTINUE READING

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