p53 post-translational modification: deregulated in tumorigenesis.

Abstract

The p53 tumor suppressor protein has well-established roles in monitoring various types of stress signals by activating specific transcriptional targets that control cell cycle arrest and apoptosis, although some activities are also mediated in a transcription-independent manner. Here, we review the recent advances in our understanding of the wide spectrum… (More)
DOI: 10.1016/j.molmed.2010.09.002

Topics

3 Figures and Tables