p53 polymorphism and p21WAF1/CIP1 haplotype in the intestinal gastric cancer and the precancerous lesions.

@article{Xi2004p53PA,
  title={p53 polymorphism and p21WAF1/CIP1 haplotype in the intestinal gastric cancer and the precancerous lesions.},
  author={Ya-Guang Xi and Ke-yue Ding and Xiu-lan Su and Dafang F. Chen and Wei-cheng You and Yan Shen and Yang Ke},
  journal={Carcinogenesis},
  year={2004},
  volume={25 11},
  pages={2201-6}
}
The development of intestinal gastric carcinoma involves several precancerous stages. The environmental factor plays an important role in gastric carcinogenesis, while the host's genetic makeup may influence the susceptibility to cancer. In this study we investigated correlations of the p53 variations at codon 72 and p21(WAF1/CIP1) haplotype with the risk of intestinal gastric carcinoma. Forty-eight intestinal gastric carcinoma cases (GC), 96 chronic atrophic gastritis (CAG), 96 intestinal… CONTINUE READING
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