p53 mutation, deprivation and poor prognosis in primary breast cancer

@article{Baker2010p53MD,
  title={p53 mutation, deprivation and poor prognosis in primary breast cancer},
  author={Lee Baker and Philip Roy Quinlan and Nancy Patten and Anna Ashfield and L-J Birse-Stewart-Bell and Colin McCowan and J-C Bourdon and C. Purdie and Lee Jordan and John A. Dewar and Ling Wu and A. M. Thompson},
  journal={British Journal of Cancer},
  year={2010},
  volume={102},
  pages={719 - 726}
}
Background:The deprivation gap for breast cancer survival remains unexplained by stage at presentation, treatment, or co-morbidities. We hypothesised that p53 mutation might contribute to the impaired outcome observed in patients from deprived communities.Methods:p53 mutation status was determined using the Roche Amplichip research test in 246 women with primary breast cancer attending a single cancer centre and related to deprivation, pathology, overall, and disease-free survival.Results:p53… CONTINUE READING