p53-induced gene 3 mediates cell death induced by glutathione peroxidase 3.


Expression of glutathione peroxidase 3 (GPx3) is down-regulated in a variety of human malignancies. Both methylation and deletion of GPx3 gene underlie the alterations of GPx3 expression in prostate cancer. A strong correlation between the down-regulation of GPx3 expression and progression of prostate cancer and the suppression of prostate cancer xenografts… (More)
DOI: 10.1074/jbc.M111.322636


Figures and Tables

Sorry, we couldn't extract any figures or tables for this paper.

Slides referencing similar topics