p53 gene alterations in special types of breast carcinoma: a molecular and immunohistochemical study in archival material.

@article{Karameris1995p53GA,
  title={p53 gene alterations in special types of breast carcinoma: a molecular and immunohistochemical study in archival material.},
  author={Andreas Karameris and Eleanor Worthy and Vassilis G Gorgoulis and Martha Quezado and O. Th. Anastassiades},
  journal={The Journal of pathology},
  year={1995},
  volume={176 4},
  pages={361-72}
}
The p53 locus on the short arm of chromosome 17 at 17p13.1 was examined for small genomic deletions and mutations in 23 formalin-fixed, paraffin-embedded cases of special types of breast carcinoma (six medullary, seven apocrine, five differentiated tubular, and five papillary). p53 mutations in the evolutionarily conserved exons 5-9 were detected in 11… CONTINUE READING