p53 expression as a prognostic marker in hepatocellular carcinoma

@inproceedings{Cioca2014p53EA,
  title={p53 expression as a prognostic marker in hepatocellular carcinoma},
  author={Andreea Cioca and Maria Cimpean and Nilima Rajpal Kundnani and Raluca Amalia Ceaușu and Cristian Suciu and Marius Raica},
  year={2014}
}
Hepatocellular carcinoma (HCC) is one of the most frequent cancers worldwide with a high mortality. Immunohistochemical overexpression of the p53 protein was correlated with a poor prognosis in various human malignancies, including HCC. In our study, 45 resected HCCs were examined to evaluate the expression of p53 and its correlation with clinicopathological parameters. Immunohistochemical detection of p53 with monoclonal human antibody, revealed its overexpression in 20 tumors (44… CONTINUE READING