p53 codon 72 polymorphism does not affect the risk of cervical cancer in patients from northern Italy.

@article{Tenti2000p53C7,
  title={p53 codon 72 polymorphism does not affect the risk of cervical cancer in patients from northern Italy.},
  author={Patrizia Tenti and Nicoletta Vesentini and M Rondo Spaudo and Rita Zappatore and Paola Migliora and Luciano Carnevali and Guglielmina Nadia Ranzani},
  journal={Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology},
  year={2000},
  volume={9 4},
  pages={435-8}
}
A case-control study was performed to investigate the risk of cervical cancer associated with p53 polymorphism at codon 72, encoding either arginine or proline. It has been recently suggested that the arginine isoform increases the susceptibility to invasive cervical cancer; however, data remain controversial. The polymorphism was examined by both allele-specific PCR and RFLP analysis in 101 patients with primary cervical cancer and in 140 healthy women of the same age and from the same… CONTINUE READING
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