p53 autoantibodies can be indicative of the development of breast cancer relapse.

@article{Regele2003p53AC,
  title={p53 autoantibodies can be indicative of the development of breast cancer relapse.},
  author={Sylvia Regele and Florian D. Vogl and Tanja Kohler and Rolf Kreienberg and I B Runnebaum},
  journal={Anticancer research},
  year={2003},
  volume={23 1B},
  pages={761-4}
}
BACKGROUND Serum autoantibodies (AAb) against mutated p53 protein have been detected in patients with invasive breast cancer of all stages. The present pilot study was conducted to investigate the use of p53 AAb titers in monitoring patients with recurrent breast cancer. PATIENTS AND METHODS Sequential sera of 24 patients with primary non-metastatic breast cancer were retrospectively ELISA-tested for the presence of p53 AAb before therapy and during the clinical follow-up until relapse… CONTINUE READING