p53 as an intervention target for cancer and aging

Abstract

p53 is well known for suppressing tumors but could also affect other aging processes not associated with tumor suppression. As a transcription factor, p53 responds to a variety of stresses to either induce apoptosis (cell death) or cell cycle arrest (cell preservation) to suppress tumor development. Yet, the effect p53 has on the non-cancer aspects of aging… (More)
DOI: 10.3402/pba.v3i0.22702

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@inproceedings{Hasty2013p53AA, title={p53 as an intervention target for cancer and aging}, author={Paul Hasty and Barbara A. Christy}, booktitle={Pathobiology of aging & age related diseases}, year={2013} }