p53 and thymidylate synthase expression in untreated stage II colon cancer: associations with recurrence, survival, and site.


We initiated a retrospective study to determine whether p53 status and thymidylate synthase (TS) protein expression in primary colon tumors influence recurrence and survival for patients with stage II colon cancer. Tumor specimens from 45 consecutive untreated patients with stage II colon cancer were examined for p53 and TS protein expression using… (More)


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