p53 and c-erbB-2 protein expression in breast carcinomas. An immunohistochemical study including correlations with receptor status, proliferation markers, and clinical stage in human breast cancer.

@article{Barbareschi1992p53AC,
  title={p53 and c-erbB-2 protein expression in breast carcinomas. An immunohistochemical study including correlations with receptor status, proliferation markers, and clinical stage in human breast cancer.},
  author={Mattia Barbareschi and Elena Leonardi and Francesco Angelo Mauri and Gabriella Serio and Paolo Dalla Palma},
  journal={American journal of clinical pathology},
  year={1992},
  volume={98 4},
  pages={408-18}
}
Receptor status, proliferative activity, loss of differentiation, inactivation of tumor suppressor genes, and overexpression of oncogenes are related events that may affect the prognosis of patients with breast cancer. Ninety-seven unselected breast carcinomas were immunostained for estrogen and progesterone receptors, Ki-67 proliferation-associated antigen, p53 tumor suppressor gene product (p53), and c-erbB-2 protein. Immunohistochemical results and clinical data were compared. Altered p53… CONTINUE READING
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