p53 and breast cancer, an update.

  title={p53 and breast cancer, an update.},
  author={M. Lacroix and R. A. Toillon and Guy Leclercq},
  journal={Endocrine-related cancer},
  volume={13 2},
p53 plays a key role in mediating cell response to various stresses, mainly by inducing or repressing a number of genes involved in cell cycle arrest, senescence, apoptosis, DNA repair, and angiogenesis. According to this important function, p53 activity is controlled in a very complex manner, including several auto-regulatory loops, through the… CONTINUE READING