p53 and bcl-2 immunohistochemistry in pretreatment prostate needle biopsies to predict recurrence of prostate cancer after radical prostatectomy.

@article{Stackhouse1999p53AB,
  title={p53 and bcl-2 immunohistochemistry in pretreatment prostate needle biopsies to predict recurrence of prostate cancer after radical prostatectomy.},
  author={G. Bennett Stackhouse and Isabell A. Sesterhenn and John J. Bauer and Fathollah K Mostofi and Roger R. Connelly and Sudhir K. Srivastava and Judd W. Moul},
  journal={The Journal of urology},
  year={1999},
  volume={162 6},
  pages={2040-5}
}
PURPOSE Immunohistochemical staining of radical prostatectomy specimens for p53 and bcl-2 proteins has been shown to correlate with prostate specific antigen (PSA) recurrence in a series of patients at our institution. We analyzed the relationship between staining of diagnostic prostate needle biopsies for p53 and bcl-2, and PSA recurrence. MATERIALS AND METHODS From 1986 to 1993, 335 radical prostatectomies were performed at our hospital. Of the prostatectomy specimens 199 had been evaluated… CONTINUE READING

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