p53 and BCL-2 as Prognostic Markers in Endometrial Carcinoma

  title={p53 and BCL-2 as Prognostic Markers in Endometrial Carcinoma},
  author={M{\'a}rcia L. M. Appel and Maria Isabel Albano Edelweiss and James D Fleck and Lu{\'i}s Fernando Rivero and Waldemar Augusto Rivoire and Heleusa Ione Monego and Ricardo Gomes dos Reis},
  journal={Pathology & Oncology Research},
The objective of this study was to verify the frequency of p53 and BCL-2 immunohistochemical expression in patients with endometrial carcinoma and to correlate it with histological factors (histological type, tumor grade, depth of myometrial invasion, lymph node involvement and surgical staging) and survival. Forty-eight patients with endometrial carcinoma who were submitted to primary surgical treatment were assessed. p53 and BCL-2 immunohistochemical expression was determined using paraffin… CONTINUE READING
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