p53 Research: the past thirty years and the next thirty years.

Abstract

Thirty years of research on the p53 family of genes has generated almost fifty thousand publications. The first of these papers detected the p53 protein associated with a viral oncogene product in transformed cells and tumors and focused the field on cancer biology. Subsequent manuscripts have shown a wide variety of functions for the p53 family of genes… (More)
DOI: 10.1101/cshperspect.a000893

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