p53 Mutation and response to hepatic arterial floxuridine in patients with colorectal liver metastases

Abstract

Purpose: To establish the relationship between the number and site of p53 genomic mutations in metastatic colorectal cancer, and the response to hepatic arterial floxuridine Methods: Liver metastasis biopsies were collected, at the time of laparotomy for hepatic arterial cannulation, in 28 patients with metachronous colorectal liver metastases. p53 Gene… (More)
DOI: 10.1007/s004320100248

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