p53 Codon 72 polymorphism and the risk of esophageal squamous cell carcinoma.

@article{Yang2008p53C7,
  title={p53 Codon 72 polymorphism and the risk of esophageal squamous cell carcinoma.},
  author={Wenjun Yang and Yanyan Zhang and Xiuyun Tian and T. Y. Ning and Yang Ke},
  journal={Molecular carcinogenesis},
  year={2008},
  volume={47 2},
  pages={100-4}
}
The polymorphisms of the tumor suppressor gene p53 have been extensively investigated in numerous malignant tumors, particularly carcinomas associated with human papillomavirus (HPV) infection. However, the results remain controversial. To address a potential correlation between the p53 genotypes and the risk of esophageal squamous cell carcinoma (ESCC), we investigated the p53 codon 72 polymorphism in 435 patients with ESCC and 550 cancer-free subjects from the same geographical region. p53… CONTINUE READING
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