p493F12 kinase: A novel MAP kinase expressed in a subset of neurons in the human nervous system

Abstract

Monoclonal antibody 3F12 identifies a cytoplasmic antigen of 49 kDa in human hippocampus and neocortex. The distribution of 3F12 immunoreactive neurons closely matches that of Alzheimer's disease (AD) targeted neurons in these areas. In some hippocampal neurons of AD patients, this antigen colocalizes with ALZ-50, indicating the presence of AD pathology in… (More)
DOI: 10.1016/0896-6273(95)90241-4

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@article{Mohit1995p493F12KA, title={p493F12 kinase: A novel MAP kinase expressed in a subset of neurons in the human nervous system}, author={Abdi A Mohit and Joel H. Martin and Carol Miller}, journal={Neuron}, year={1995}, volume={14}, pages={67-78} }