p44/42 mitogen-activated protein kinase is involved in the expression of ornithine decarboxylase in leukaemia L1210 cells.

Abstract

The involvement of p44/42 mitogen-activated protein kinase (MAPK) in the induction of ornithine decarboxylase (ODC) was investigated by using PD98059, a specific MAPK-kinase (MEK1/2) inhibitor, and other signal-transduction inhibitors. In d,l-alpha-difluoromethylornithine (DFMO)-resistant L1210 cells stimulated to grow from quiescence, treatment with… (More)

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@article{Flamigni1999p4442MP, title={p44/42 mitogen-activated protein kinase is involved in the expression of ornithine decarboxylase in leukaemia L1210 cells.}, author={Flavio Flamigni and Annalisa Facchini and Cristina Capanni and Claudio Stefanelli and Benedetta Tantini and Claudio Marcello Caldarera}, journal={The Biochemical journal}, year={1999}, volume={341 ( Pt 2)}, pages={363-9} }