p38 mitogen-activated protein kinase regulates mitochondrial function and microvesicle release in riboflavin- and ultraviolet light-treated apheresis platelet concentrates.

Abstract

BACKGROUND Biochemical analyses of mechanisms triggered in platelets (PLTs) upon pathogen inactivation (PI) are crucial to further understand the impact of PI on PLT functionality and, subsequently, quality. STUDY DESIGN AND METHODS PLT concentrates (PCs) were split into four small illumination bags: 1) untreated control, 2) treated with riboflavin and… (More)
DOI: 10.1111/trf.14035

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