p38 MAPK signaling mediates mitochondrial apoptosis in cancer cells induced by oleanolic acid.

Oleanolic acid (OA) is a nutritional component widely distributed in various vegetables. Although it has been well recognized for decades that OA exerts certain anti-tumor activity by inducing mitochondria-dependent apoptosis, it is still unclear that what molecular signaling is responsible for this effect. In this study, we employed cancer cell lines, A549… CONTINUE READING

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