p38 MAPK Regulates Cavitation and Tight Junction Function in the Mouse Blastocyst

  title={p38 MAPK Regulates Cavitation and Tight Junction Function in the Mouse Blastocyst},
  author={Christine Elizabeth Bell and Andrew J Watson},
  booktitle={PloS one},
UNLABELLED Blastocyst formation is essential for implantation and maintenance of pregnancy and is dependent on the expression and coordinated function of a series of proteins involved in establishing and maintaining the trans-trophectoderm ion gradient that enables blastocyst expansion. These consist of Na/K-ATPase, adherens junctions, tight junctions (TJ) and aquaporins (AQP). While their role in supporting blastocyst formation is established, the intracellular signaling pathways that… CONTINUE READING


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