p38 MAPK Participates in Muscle-Specific RING Finger 1-Mediated Atrophy in Cast-Immobilized Rat Gastrocnemius Muscle.

@article{Kim2009p38MP,
  title={p38 MAPK Participates in Muscle-Specific RING Finger 1-Mediated Atrophy in Cast-Immobilized Rat Gastrocnemius Muscle.},
  author={Junghwan Kim and K. Won and Hwan Myung Lee and Byong-yong Hwang and Y. Bae and W. Choi and Hyuk Song and Ki Won Lim and Chang-Kwon Lee and Bokyung Kim},
  journal={The Korean journal of physiology \& pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology},
  year={2009},
  volume={13 6},
  pages={
          491-6
        }
}
  • Junghwan Kim, K. Won, +7 authors Bokyung Kim
  • Published 2009
  • Medicine
  • The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology
Skeletal muscle atrophy is a common phenomenon during the prolonged muscle disuse caused by cast immobilization, extended aging states, bed rest, space flight, or other factors. However, the cellular mechanisms of the atrophic process are poorly understood. In this study, we investigated the involvement of mitogen-activated protein kinase (MAPK) in the expression of muscle-specific RING finger 1 (MuRF1) during atrophy of the rat gastrocnemius muscle. Histological analysis revealed that cast… Expand
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