p300 modulates nuclear morphology in prostate cancer.

@article{Debes2005p300MN,
  title={p300 modulates nuclear morphology in prostate cancer.},
  author={Jose D. Debes and Thomas J. Sebo and Hannelore V. Heemers and Benjamin R. Kipp and De Anna L. Haugen and Christine Marie Lohse and Donald J. Tindall},
  journal={Cancer research},
  year={2005},
  volume={65 3},
  pages={708-12}
}
Alterations in nuclear structure distinguish cancer cells from noncancer cells. These nuclear alterations can be translated into quantifiable features by digital image analysis in a process known as quantitative nuclear morphometry. Recently, quantitative nuclear morphometry has been shown to predict metastasis and biochemical recurrence of prostate cancer. However, little is known about the cellular mechanisms underlying these nuclear morphometric changes. Alterations of nuclear matrix… CONTINUE READING
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biomarker

  • AR Ramsden, G Chodak
  • 2004

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