p300/CBP acts as a coactivator of the cone-rod homeobox transcription factor.

@article{Yanagi2000p300CBPAA,
  title={p300/CBP acts as a coactivator of the cone-rod homeobox transcription factor.},
  author={Yasuo Yanagi and Yoshikazu Masuhiro and Masaki Mori and Junn Yanagisawa and Shigeaki Kato},
  journal={Biochemical and biophysical research communications},
  year={2000},
  volume={269 2},
  pages={410-4}
}
CRX (cone-rod homeobox) is shown to play an important role on the photoreceptor cell maturation and maintenance. However, little is known about the molecular mechanism how CRX potentiates transcription. Here, we investigated the effect of several coactivators (p300/CBP, SRC-1, TIF2, and AIB1) on the transactivation function of CRX. The transient expression… CONTINUE READING