p21-activated protein kinase gamma-PAK in pituitary secretory granules phosphorylates prolactin.

Abstract

p21-activated protein kinase gamma-PAK phosphorylates prolactin (PRL) in rat pituitary secretory granules on Ser-177 and on the equivalent site, Ser-179, in recombinant human PRL. This is shown by comparison of phosphopeptide maps with the human PRL mutant S179D. gamma-PAK is present in rat and bovine granules as identified by in-gel phosphorylation of… (More)

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@article{Tuazon2002p21activatedPK, title={p21-activated protein kinase gamma-PAK in pituitary secretory granules phosphorylates prolactin.}, author={Polygena T. Tuazon and Mary Y. Lorenson and Ameae M. Walker and Jolinda A. Traugh}, journal={FEBS letters}, year={2002}, volume={515 1-3}, pages={84-8} }