p202 levels are negatively regulated by serum growth factors.

  title={p202 levels are negatively regulated by serum growth factors.},
  author={Yun-qi Geng and Sanjay D'Souza and Hong Xin and Scott R. Walter and Divaker Choubey},
  journal={Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research},
  volume={11 9},
p202 is an IFN-inducible phosphoprotein (Mr 52,000) whose expression in transfected cells retards proliferation. Interestingly, the reduced levels of p202 in fibroblasts (in consequence of the expression of antisense to 202 RNA), under reduced serum conditions, increase the susceptibility of cells to apoptosis. To identify the functional role of p202 in cell growth regulation, we tested whether serum growth factor levels in the culture medium affect p202 levels. Here we report that, under… CONTINUE READING