p16 ink4a and HPV L1 immunohistochemistry is helpful for estimating the behavior of low-grade dysplastic lesions of the cervix uteri.

@article{Negri2008p16IA,
  title={p16 ink4a and HPV L1 immunohistochemistry is helpful for estimating the behavior of low-grade dysplastic lesions of the cervix uteri.},
  author={Giovanni Negri and Giulia Bellisano and Gian Franco Zannoni and Francesco Rivasi and Armin Kasal and F Vittadello and Sonia Antoniazzi and Gavino Faa and Rossano Ambu and Eduard Egarter-Vigl},
  journal={The American journal of surgical pathology},
  year={2008},
  volume={32 11},
  pages={1715-20}
}
As only a minority of low-grade dysplastic lesions of the cervix uteri will eventually progress to carcinoma, predicting the behavior of these lesions could be of high value in clinical practice. The aim of the study was to evaluate p16 ink4a and L1 as immunohistochemical markers of the biologic potentiality of low-grade dysplasia of the uterine cervix. The study included 38 conization specimens with coexisting cervical intraepithelial neoplasia grade 1 (CIN1) and 3 (CIN3) (group A) and 28… CONTINUE READING
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