p16 expression in conventional and desmoplastic trichilemmomas.

  title={p16 expression in conventional and desmoplastic trichilemmomas.},
  author={Nicholaus J Hilliard and Dara N Wakefield and Dieter Krahl and Klaus Sellheyer},
  journal={The American Journal of dermatopathology},
  volume={31 4},
The expression of p16 in cutaneous neoplasms is upregulated in melanocytic neoplasms, ultraviolet radiation-induced neoplasms, such as actinic keratoses and squamous cell carcinomas, and in lesions related to human papillomavirus, such as Bowen's disease and bowenoid papulosis. In cervical dysplasia and tonsillar carcinoma, there is such a close relationship between p16 and human papillomavirus (HPV) to the extent that p16 immunostaining is used as a surrogate marker for the presence of HPV… CONTINUE READING