p16/CDKN2A FISH in Differentiation of Diffuse Malignant Peritoneal Mesothelioma From Mesothelial Hyperplasia and Epithelial Ovarian Cancer.

@article{Ito2015p16CDKN2AFI,
  title={p16/CDKN2A FISH in Differentiation of Diffuse Malignant Peritoneal Mesothelioma From Mesothelial Hyperplasia and Epithelial Ovarian Cancer.},
  author={Tomohiro Ito and Makoto Hamasaki and Shinji Matsumoto and Kenzo Hiroshima and Tohru Tsujimura and Toshiaki Kawai and Yoshiya Shimao and Kousuke Marutsuka and Sayaka Moriguchi and Riruke Maruyama and Shingo Miyamoto and Kazuki Nabeshima},
  journal={American journal of clinical pathology},
  year={2015},
  volume={143 6},
  pages={830-8}
}
OBJECTIVES It can be difficult to differentiate diffuse malignant peritoneal mesothelioma (DMPM) from reactive mesothelial hyperplasia (RMH) or peritoneal dissemination of gynecologic malignancies, such as epithelial ovarian cancer (EOC), which cause a large amount of ascites. Detection of the homozygous deletion of p16/CDKN2A (p16) by fluorescence in situ… CONTINUE READING