p125Fak focal adhesion kinase is a substrate for the insulin and insulin-like growth factor-I tyrosine kinase receptors.

@article{Baron1998p125FakFA,
  title={p125Fak focal adhesion kinase is a substrate for the insulin and insulin-like growth factor-I tyrosine kinase receptors.},
  author={V{\'e}ronique T Baron and V{\'e}ronique Calleja and Paul L Ferrari and Franc Oise Alengrin and E Van Obberghen},
  journal={The Journal of biological chemistry},
  year={1998},
  volume={273 12},
  pages={7162-8}
}
The focal adhesion kinase p125(Fak) is a widely expressed cytosolic tyrosine kinase, which is involved in integrin signaling and in signal transduction of a number of growth factors. In contrast to tyrosine kinase receptors such as the platelet-derived growth factor and the hepatocyte growth factor receptors, which induce p125(Fak) phosphorylation, insulin has been shown to promote its dephosphorylation. In this study, we compared p125(Fak) phosphorylation in insulin-stimulated cells maintained… CONTINUE READING
41 Citations
1 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 41 extracted citations

References

Publications referenced by this paper.

hp://w w w .jb.org/ D ow nladed from Van Obberghen

  • P. S. Leventhal, E. A. Shelden, B. Kim, E. L. Feldman
  • J. Biol. Chem
  • 1997

Similar Papers

Loading similar papers…