• Biology
• Published 2003
• DOI:10.1128/MCB.23.7.2287-2297.2003

p120 Catenin-Associated Fer and Fyn Tyrosine Kinases Regulate β-Catenin Tyr-142 Phosphorylation and β-Catenin-α-Catenin Interaction

@inproceedings{Piedra2003p120CF,
  title={p120 Catenin-Associated Fer and Fyn Tyrosine Kinases Regulate β-Catenin Tyr-142 Phosphorylation and β-Catenin-α-Catenin Interaction},
  author={Jos{\'e} Piedra and Susana Miravet and Julio Casta{\~n}o and H{\'e}ctor G. P{\'a}lmer and Nora Heisterkamp and Antonio Garc{\'i}a de Herreros and Mireia Du{\~n}ach},
  year={2003}
}

• José Piedra, Susana Miravet, +4 authors Mireia Duñach

Cell-cell contacts among epithelial cells have a crucial function in organized tissues and are mainly mediated by adherens junctions and desmosomes. In adherens junctions, although the extracellular domain of E-cadherin is essential for connecting cells through homophilic interactions, its intracellular domain is required for regulating cell-cell adhesion. The latter domain is indirectly associated with the actin cytoskeleton through either β-catenin or plakoglobin and α-catenin. These… CONTINUE READING

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