• Published 2015

p 53 regulates expression of uncoupling protein 1 through binding and repression of PPAR γ coactivator 1 α 1 2

@inproceedings{Hallenborg2015p5R,
  title={p 53 regulates expression of uncoupling protein 1 through binding and repression of PPAR γ coactivator 1 α 1 2},
  author={Philip Hallenborg and Even Fj{\ae}re and Bj{\o}rn Liaset and Rasmus K. Petersen and Incoronata Murano and Brask Sonne and Mathias Falkerslev and Sally Winther and Benjamin Anderschou Holbech Jensen and Tao Ma and Jacob Bjerg Hansen and Saverio Cinti and Blagoy Blagoev and Lise Madsen and Karsten Kristiansen},
  year={2015}
}
33 The tumor suppressor p53 (TRP53 in mice) is 34 known for its involvement in carcinogenesis, but 35 work during recent years has underscored the 36 importance of p53 in the regulation of whole 37 body metabolism. A general notion is that p53 is 38 necessary for efficient oxidative metabolism. The 39 importance of UCP1-dependent uncoupled 40 respiration and increased oxidation of glucose 41 and fatty acids in brown or brown-like, termed 42 BRITE or beige, adipocytes in relation to energy 43… CONTINUE READING

References

Publications referenced by this paper.

A catalog of the mouse gut metagenome