p,p'-DDE disturbs the homeostasis of thyroid hormones via thyroid hormone receptors, transthyretin, and hepatic enzymes.

@article{Liu2011ppDDEDT,
  title={p,p'-DDE disturbs the homeostasis of thyroid hormones via thyroid hormone receptors, transthyretin, and hepatic enzymes.},
  author={Chaoyuan Liu and Y. Shi and Hong-Bo Li and Y Wang and Kedi Yang},
  journal={Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme},
  year={2011},
  volume={43 6},
  pages={391-6}
}
1,1-Dichloro-2,2-bis(p-chlorophenyl)ethylene (p, p'-dichlorodiphenyldichloroethylene, p, p'-DDE), the major metabolite of 2,2-bis(p-chlorophenyl)-1,1,1-trichloroethane (DDT), is a known persistent organic pollutant and endocrine disrupting toxicant. In recent years, it has attracted many attentions on account of its disturbing effects on thyroid and thyroid hormones (THs). However, the mechanisms by which the p, p'-DDE exposure influences THs still remain uncertain. To elucidate the possible… CONTINUE READING
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