oxLDL-Induced Lipid Accumulation in Glomerular Podocytes: Role of IFN-γ, CXCL16, and ADAM10

@article{Wang2014oxLDLInducedLA,
  title={oxLDL-Induced Lipid Accumulation in Glomerular Podocytes: Role of IFN-γ, CXCL16, and ADAM10},
  author={Li Wang and Shuzhen Sun and Aihua H Zhou and Xiujun Yao and Yulin Wang},
  journal={Cell Biochemistry and Biophysics},
  year={2014},
  volume={70},
  pages={529-538}
}
Previous studies have shown that lipid accumulation plays an important role in the pathogenesis and development of glomerular sclerosis. oxLDL caused damage in renal mesangial cells, endothelial cells, and podocytes, and podocytes might be the major victim of oxLDL insult. However, the regulatory mechanism of how oxLDL induces the damage of podocytes… CONTINUE READING