• Corpus ID: 14472834

nterstitial fluid glucose time-lag correction for real-time continuous glucose onitoring

  title={nterstitial fluid glucose time-lag correction for real-time continuous glucose onitoring},
  author={Barry Keenana and John J. Mastrototaroa and Stuart A. Weinzimerb and Garry M. Steil},
Time lag between subcutaneous interstitial fluid and plasma glucose decreases the accuracy of realtime continuous glucose monitors. However, inverse filters can be designed to correct time lag and attenuate noise enabling the blood–glucose profile to be reconstructed in real time from continuous measurements of the interstitial-fluid glucose. We designed and tested a Wiener filter using a set of 20 sensor-glucose tracings (∼30 h each) with a 1-min sample interval. Delays of 10 ± 2 min (mean… 

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