neu mutation in schwannomas induced transplacentally in Syrian golden hamsters by N-nitrosoethylurea: high incidence but low allelic representation

@article{Buzard1999neuMI,
  title={neu mutation in schwannomas induced transplacentally in Syrian golden hamsters by N-nitrosoethylurea: high incidence but low allelic representation},
  author={Gregory S. Buzard and Takayuki Enomoto and Tadashi Hongyo and Alan O Perantoni and Bhalchandra A. Diwan and Deborah E. Devor and Carl D. Reed and Lee F. Dove and Jerry M. Rice},
  journal={Journal of Cancer Research and Clinical Oncology},
  year={1999},
  volume={125},
  pages={529-540}
}
Abstract Peripheral nerve tumors (PNT) and melanomas induced transplacentally on day 14 of gestation in Syrian golden hamsters by N-nitrosoethylurea were analyzed for activated oncogenes by the NIH 3T3 transfection assay, and for mutations in the neu oncogene by direct sequencing, allele-specific oligonucleotide hybridization, MnlI restriction-fragment-length polymorphism, single-strand conformation polymorphism, and mismatch amplification mutation assays. All (67/67) of the PNT, but none of… CONTINUE READING

References

Publications referenced by this paper.
SHOWING 1-10 OF 56 REFERENCES

Specific patterns of oncogene activation in transplacentally induced tumors.

  • Proceedings of the National Academy of Sciences of the United States of America
  • 1990
VIEW 14 EXCERPTS
HIGHLY INFLUENTIAL

Increased tyrosine kinase activity associated with the protein encoded by the activated neu oncogene.

  • Proceedings of the National Academy of Sciences of the United States of America
  • 1988
VIEW 5 EXCERPTS
HIGHLY INFLUENTIAL

tations and loss of normal allele in schwannomas induced by N - ethyl - N - nitrosourea in rats

AO Perantoni, JM Rice, CD Reed, M Watatani, ML Wenk
  • Cancer Lett
  • 1987
VIEW 5 EXCERPTS
HIGHLY INFLUENTIAL

Specificity within the EGF family/ErbB receptor family signaling network.

  • BioEssays : news and reviews in molecular, cellular and developmental biology
  • 1998