neXtProt: organizing protein knowledge in the context of human proteome projects.

  title={neXtProt: organizing protein knowledge in the context of human proteome projects.},
  author={Pascale Gaudet and Ghislaine Argoud-Puy and Isabelle Cusin and Paula D. Duek and Olivier Evalet and Alain Gateau and Anne Gleizes and Mario Pereira and Monique Zahn-Zabal and Catherine Zwahlen and Amos Bairoch and Lydie Lane},
  journal={Journal of proteome research},
  volume={12 1},
About 5000 (25%) of the ~20400 human protein-coding genes currently lack any experimental evidence at the protein level. For many others, there is only little information relative to their abundance, distribution, subcellular localization, interactions, or cellular functions. The aim of the HUPO Human Proteome Project (HPP, ) is to collect this information for every human protein. HPP is based on three major pillars: mass spectrometry (MS), antibody/affinity capture reagents (Ab… CONTINUE READING


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