nduction and control of the type I interferon pathway by Bluetongue irus

@inproceedings{Vitour2017nductionAC,
  title={nduction and control of the type I interferon pathway by Bluetongue irus},
  author={Damien Vitour and Virginie Doceul and Suzana Ruscanu and Emilie Chauveau and Isabelle Schwartz and St{\'e}phan Zientara},
  year={2017}
}
The innate immune response is the first line of defence against viruses, involving the production of type I IFN (IFN/ ) and other pro-inflammatory cytokines that control the infection. It also shapes the adaptive immune response generated by both T and B cells. Production of type I IFN occurs both in vivo and in vitro in response to Bluetongue virus (BTV), an arthropod-borne virus. However, the mechanisms responsible for the production of IFNin response to BTV remained unknown until recently… CONTINUE READING

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