n-3 polyunsaturated fatty acids and insulin secretion.


n-3 polyunsaturated fatty acids (PUFAs) are a subgroup of fatty acids with broad health benefits, such as lowering blood triglycerides and decreasing the risk of some types of cancer. A beneficial effect of n-3 PUFAs in diabetes is indicated by results from some studies. Defective insulin secretion is a fundamental pathophysiological change in both types 1 and 2 diabetes. Emerging studies have provided evidence of a connection between n-3 PUFAs and improved insulin secretion from pancreatic β-cells. This review summarizes the recent findings in this regard and discusses the potential mechanisms by which n-3 PUFAs influence insulin secretion from pancreatic β-cells.

DOI: 10.1530/JOE-14-0581

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@article{Wang2015n3PF, title={n-3 polyunsaturated fatty acids and insulin secretion.}, author={Xiaofeng Wang and Catherine B. Chan}, journal={The Journal of endocrinology}, year={2015}, volume={224 3}, pages={R97-106} }