mu-opioid receptor-mediated antinociceptive responses differ in men and women.

@article{Zubieta2002muopioidRA,
  title={mu-opioid receptor-mediated antinociceptive responses differ in men and women.},
  author={J K Zubieta and Yolanda R. Smith and Joshua A. Bueller and Yanjun Xu and Michael R. Kilbourn and Douglas M. Jewett and Charles R. Meyer and Robert A. Koeppe and Christian S. Stohler},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={2002},
  volume={22 12},
  pages={5100-7}
}
Sex differences in the experience of clinical and experimental pain have been reported. However, the neurobiological sources underlying the variability in pain responses between sexes have not been adequately explored, especially in humans. The endogenous opioid neurotransmitters and mu-opioid receptors are centrally implicated in responses to stress, in the suppression of pain, and in the action of opiate analgesic drugs. Here we examined sex differences in the activation of the mu-opioid… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 71 extracted citations

Amygdala functional connectivity is reduced after the cold pressor task.

Cognitive, affective & behavioral neuroscience • 2013
View 4 Excerpts
Highly Influenced

Imaging of opioid receptors in the central nervous system

Brain : a journal of neurology • 2008
View 3 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…