mtDNA Mutations and Their Role in Aging, Diseases and Forensic Sciences.

Abstract

Mitochondria are independent organelles with their own DNA. As a primary function, mitochondria produce the energy for the cell through Oxidative Phosphorylation (OXPHOS) in the Electron Transport Chain (ETC). One of the toxic products of this process is Reactive Oxygen Species (ROS), which can induce oxidative damage in macromolecules like lipids, proteins… (More)
DOI: 10.14336/AD.2013.0400364

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