monoamine oxidase inhibitors revisited

@article{Wells1989monoamineOI,
  title={monoamine oxidase inhibitors revisited},
  author={Douglas G. Wells and Andrew R. Bjorksten},
  journal={Canadian Journal of Anaesthesia},
  year={1989},
  volume={36},
  pages={64-74}
}
ConclusionUntil recently, traditional teaching has been to discontinue MAOI therapy two to three weeks before surgery. The literature and texts relating to the concurrent use of MAOI’s with anaesthesia are confusing, outdated and often contradictory. Significant adverse drug reactions can and have occurred in a minority of patients receiving MAOI’s. The true incidence of such reactions is unknown. While there are several recent clinical reports indicating the safety of these agents in… 
Anesthesia and Monoamine Oxidase Inhibitors-Reply
TLDR
It is now time to reevaluate the traditional sentiment regarding discontinuation of monoamine oxidase inhibitors (MAOIs) 2 to 3 weeks prior to elective surgery because of cardiovascular instability and central nervous system dysfunction during anesthesia.
MAOIs to RIMAs in anaesthesia — a literature review
TLDR
This review suggests that combination of modern anaesthetic techniques and newer, specific reversible MAOIs should allow safe anaesthesia with maintenance of antidepressant therapy.
Serotonin syndrome due to venlafaxine and maintenance tranylcypromine therapy
TLDR
The development of the serotonin syndrome is described in a 60 year old female on chronic tranylcypromine treatment following the inadvertent ingestion of a single dose of venlafaxine, leading to an altered mental status that progressed to hyperthermia and coma.
MAO inhibitors and coronary artery surgery: a patient death
  • W. Noble, A. Baker
  • Medicine
    Canadian journal of anaesthesia = Journal canadien d'anesthesie
  • 1992
TLDR
It is concluded that MAOIs should be discontinued, if possible, before surgery in which catecholamines may be needed, because of the unusual reactions inpatients while taking both meperidine andMAOIs.
Cardiac surgery in a patient taking monoamine oxidase inhibitors: an adverse fentanyl reaction.
TLDR
There are 12 case reports in the world literature implicating the combination of meperidine and MAOIs as potentially fatal, this being related to an inhibition of 5-hydroxytryptamine (5-HT) uptake by both the opioid and MA01 in the brain leading to increased levels of 4-HT at the synaptic cleft and consequent adverse reactions including hyperpyrexia, hypertension, hypotension, tachycardia, or convulsions.
The Role of Monoamine Oxidase Inhibitors in Current Psychiatric Practice
TLDR
Clinicians must continue to familiarize themselves with the properties of and indications for prescribing MAOIs and identify symptom presentations more likely to respond to these medications.
Dietary restrictions and drug interactions with monoamine oxidase inhibitors: the state of the art.
  • M. Rapaport
  • Psychology, Medicine
    The Journal of clinical psychiatry
  • 2007
TLDR
MAOIs have been well established as an effective intervention for people with treatment-resistant depression, and transdermal formulations may provide a valuable therapeutic option and eliminate the drug-food interaction.
Kingston General Hospital
TLDR
The classic MAOI, phenelzine and tranylcypromine, irreversibly inhibit MAO for 2 to 3 weeks until new enzyme is synthesized, and suitability of these patients for ambulatory anesthesia has been controversial.
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References

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TLDR
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TLDR
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TLDR
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TLDR
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TLDR
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TLDR
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