mitoEnergetics and cancer cell fate.

  title={mitoEnergetics and cancer cell fate.},
  author={Zhi Xiong Chen and Rathiga Velaithan and Shazib Pervaiz},
  journal={Biochimica et biophysica acta},
  volume={1787 5},
The critical role of mitochondria in cell fate decisions has been well documented over the years. These observations have highlighted the way mitochondrial physiology controls cell survival and growth in the normal settings, the critical role of mitochondrial outer membrane permeabilization and altered mitoenergetics in cell death execution, and most importantly the association of altered mitochondrial metabolism with pathological states, in particular cancer. Reprogramming of cell metabolism… CONTINUE READING