mir-21 Overexpressing Mesenchymal Stem Cells Accelerate Fracture Healing in a Rat Closed Femur Fracture Model

@inproceedings{Sun2015mir21OM,
  title={mir-21 Overexpressing Mesenchymal Stem Cells Accelerate Fracture Healing in a Rat Closed Femur Fracture Model},
  author={Yu-Xin Sun and Liangliang Xu and Shuo Huang and Yonghui Hou and Yang Liu and Kai-ming Chan and Xiao-hua Pan and Gang Li},
  booktitle={BioMed research international},
  year={2015}
}
MicroRNAs are small noncoding RNAs involved in numerous biological processes. Emerging pieces of evidence suggest that microRNAs play important roles in osteogenesis and skeletal homeostasis. Recent studies indicated the significant regulation function of mir-21 in osteogenesis in vitro, but little information is known about its veritable functions in vivo. In the present study, we aimed to investigate the effect of mir-21 intervention on osteogenic differentiation of rats bone marrow derived… CONTINUE READING
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