mir-17-92, a cluster of miRNAs in the midst of the cancer network.

@article{Olive2010mir1792AC,
  title={mir-17-92, a cluster of miRNAs in the midst of the cancer network.},
  author={Virginie Olive and Iris Jiang and Lin He},
  journal={The international journal of biochemistry & cell biology},
  year={2010},
  volume={42 8},
  pages={
          1348-54
        }
}
MicroRNAs (miRNAs) are an abundant class of small non-coding RNAs (ncRNAs) that function to regulate gene expression at the post-transcriptional level. Although their functions were originally described during normal development, miRNAs have emerged as integral components of the oncogenic and tumor suppressor network, regulating nearly all cellular processes altered during tumor formation. In particular, mir-17-92, a miRNA polycistron also known as oncomir-1, is among the most potent oncogenic… CONTINUE READING
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